Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANKRD28Ankyrin repeat domain 28. (1082 aa)    
Predicted Functional Partners:
PPP6C
Serine/threonine-protein phosphatase.
    
 0.917
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
   
 0.902
PPP6R2
Protein phosphatase 6 regulatory subunit 2.
   
 0.899
PPP6R3
Protein phosphatase 6 regulatory subunit 3.
   
 0.845
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
   0.662
RPP40
Ribonuclease P/MRP subunit p40.
   
 0.559
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
    
 0.558
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
    
 0.550
ZNRF2
RING-type domain-containing protein.
    
 
 0.535
RHBDD2
Rhomboid domain containing 2.
    
 0.529
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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