Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTPN1Protein tyrosine phosphatase non-receptor type 1. (495 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.994
JAK2
Tyrosine-protein kinase.
   
 0.976
EGFR
Receptor protein-tyrosine kinase.
    
 0.957
IGF1R
Tyrosine-protein kinase receptor.
    
 0.936
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
0.927
INSRR
Tyrosine-protein kinase receptor.
    
 0.921
CTNNB1
Catenin beta 1.
    
 0.920
TYK2
Non-specific protein-tyrosine kinase.
   
 0.895
MST1R
Macrophage stimulating 1 receptor.
    
 0.879
PTPRF
Protein tyrosine phosphatase receptor type F.
   
 0.874
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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