DLX6 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

DLX6

Distal-less homeobox 6. (164 aa)

Predicted Functional Partners:

DLX5

0.851

BMP4

0.568

RUNX2

0.559

GAD2

0.558

BMP2

0.552

GAD1

0.546

HAND2

0.540

SST

0.485

ST8SIA4

0.477

MECP2

0.469

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP4	ENSOCUP00000010036	ENSOCUP00000009545	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.874
BMP2	DLX5	ENSOCUP00000010036	ENSOCUP00000037071	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	Distal-less homeobox 5.	0.797
BMP2	DLX6	ENSOCUP00000010036	ENSOCUP00000007444	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	Distal-less homeobox 6.	0.552
BMP2	RUNX2	ENSOCUP00000010036	ENSOCUP00000010093	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	RUNX family transcription factor 2.	0.914
BMP4	BMP2	ENSOCUP00000009545	ENSOCUP00000010036	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	0.874
BMP4	DLX5	ENSOCUP00000009545	ENSOCUP00000037071	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Distal-less homeobox 5.	0.821
BMP4	DLX6	ENSOCUP00000009545	ENSOCUP00000007444	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Distal-less homeobox 6.	0.568
BMP4	HAND2	ENSOCUP00000009545	ENSOCUP00000013968	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	BHLH domain-containing protein.	0.570
BMP4	RUNX2	ENSOCUP00000009545	ENSOCUP00000010093	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	RUNX family transcription factor 2.	0.832
DLX5	BMP2	ENSOCUP00000037071	ENSOCUP00000010036	Distal-less homeobox 5.	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	0.797
DLX5	BMP4	ENSOCUP00000037071	ENSOCUP00000009545	Distal-less homeobox 5.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.821
DLX5	DLX6	ENSOCUP00000037071	ENSOCUP00000007444	Distal-less homeobox 5.	Distal-less homeobox 6.	0.851
DLX5	GAD1	ENSOCUP00000037071	ENSOCUP00000035362	Distal-less homeobox 5.	Glutamate decarboxylase 1.	0.569
DLX5	GAD2	ENSOCUP00000037071	ENSOCUP00000015017	Distal-less homeobox 5.	Glutamate decarboxylase 2.	0.566
DLX5	HAND2	ENSOCUP00000037071	ENSOCUP00000013968	Distal-less homeobox 5.	BHLH domain-containing protein.	0.630
DLX5	MECP2	ENSOCUP00000037071	ENSOCUP00000048554	Distal-less homeobox 5.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.566
DLX5	RUNX2	ENSOCUP00000037071	ENSOCUP00000010093	Distal-less homeobox 5.	RUNX family transcription factor 2.	0.860
DLX5	SST	ENSOCUP00000037071	ENSOCUP00000006540	Distal-less homeobox 5.	Somatostatin.	0.548
DLX6	BMP2	ENSOCUP00000007444	ENSOCUP00000010036	Distal-less homeobox 6.	Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.	0.552
DLX6	BMP4	ENSOCUP00000007444	ENSOCUP00000009545	Distal-less homeobox 6.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.568