Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MVPMajor vault protein. (890 aa)    
Predicted Functional Partners:
PARP4
Poly [ADP-ribose] polymerase.
   
 
 0.960
TEP1
Telomerase associated protein 1.
   
 
 0.901
COP1
COP1 E3 ubiquitin ligase.
    
   0.689
ANLN
Anillin actin binding protein.
    
   0.570
JMJD6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
    
 
 0.544
MACROD2
Mono-ADP ribosylhydrolase 2.
      
 0.496
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 
 0.479
CTSF
Cathepsin F; Belongs to the peptidase C1 family.
      
 0.473
APAF1
Apoptotic peptidase activating factor 1.
    
 
 0.470
PARP14
Poly [ADP-ribose] polymerase.
   
  
 0.467
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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