STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WFDC13WAP four-disulfide core domain 13. (93 aa)    
Predicted Functional Partners:
WFDC9
WAP four-disulfide core domain 9.
      
 0.887
OVCH2
Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family.
    
 0.763
ADAM28
ADAM metallopeptidase domain 28.
     
 0.681
PLA2G2D
Phospholipase A(2).
      
 0.616
LOC100346323
Uncharacterized protein.
   
 0.574
SPINT4
Serine peptidase inhibitor, Kunitz type 4.
   
 
 0.551
SORL1
Sortilin-related receptor; Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism. Does not affect APP trafficking from the endoplasmic r [...]
    
 0.520
WFDC11
WAP four-disulfide core domain 11.
    
 
 0.497
WFDC3
Uncharacterized protein.
   
 
 0.465
WAP
Whey acidic protein; Could be a protease inhibitor.
   
 
 0.465
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.