Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAMD7Sterile alpha motif domain containing 7. (448 aa)    
Predicted Functional Partners:
SAMD14
Sterile alpha motif domain containing 14.
      
 0.712
OPN1SW
Opsin 1, short wave sensitive.
      
 0.706
SMAD7
Mothers against decapentaplegic homolog.
      
 0.682
GPR160
G protein-coupled receptor 160.
      
 0.656
SCML2
Scm polycomb group protein like 2.
   
 
 0.515
SEC62
SEC62 homolog, preprotein translocation factor.
 
    
 0.491
SCML4
SAM domain-containing protein.
   
  
 0.484
ATP1A1
Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (By similarity). May contribute to blood-heart barrier properties of endocardial endothelium and may control cardiac performance via endothelial Na(+)/H(+) exchange.
      
 0.479
ATP1A2
Sodium/potassium-transporting ATPase subunit alpha.
      
 0.479
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
 0.467
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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