Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPINK5Serine peptidase inhibitor, Kazal type 5. (1087 aa)    
Predicted Functional Partners:
KLK5
Kallikrein related peptidase 5; Belongs to the peptidase S1 family.
   
 0.980
DSG1
Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
  
 0.745
CRNN
Cornulin.
  
  
 0.734
CDSN
Corneodesmosin.
      
 0.702
KLK7
Kallikrein related peptidase 7; Belongs to the peptidase S1 family.
   
 0.692
KRTDAP
Keratinocyte differentiation associated protein.
   
  
 0.640
ST14
Suppression of tumorigenicity 14.
    
 0.619
G1TH80_RABIT
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.599
NIPAL4
NIPA like domain containing 4.
      
 0.591
ENSOCUP00000032555
Uncharacterized protein.
   
 
 0.583
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (20%) [HD]