Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMT2ELysine methyltransferase 2E. (1475 aa)    
Predicted Functional Partners:
SETD2
Uncharacterized protein.
   
 0.957
ASH1L
ASH1 like histone lysine methyltransferase.
   
 0.928
SMYD2
SET and MYND domain containing 2.
    
 0.912
KMT5B
Lysine methyltransferase 5B.
     
 0.899
SMYD3
SET and MYND domain containing 3.
    
 0.896
NSD3
Nuclear receptor binding SET domain protein 3.
   
 0.892
SMYD1
SET and MYND domain containing 1.
    
 0.885
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
    
 0.880
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
    
 0.871
SETD5
SET domain containing 5.
   
0.871
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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