POF1B protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

POF1B

POF1B actin binding protein. (590 aa)

Predicted Functional Partners:

KIAA1191

0.768

AMER2

0.735

FIGLA

0.728

NOBOX

0.710

LIMCH1

0.693

BMP15

0.666

ERICH6

0.649

TMPO

0.604

DIAPH2

0.590

TMOD1

0.583

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMER2	POF1B	ENSOCUP00000006574	ENSOCUP00000007613	APC membrane recruitment protein 2.	POF1B actin binding protein.	0.735
BMP15	FIGLA	ENSOCUP00000020965	ENSOCUP00000014858	TGF_BETA_2 domain-containing protein.	Folliculogenesis specific bHLH transcription factor.	0.855
BMP15	NOBOX	ENSOCUP00000020965	ENSOCUP00000000887	TGF_BETA_2 domain-containing protein.	NOBOX oogenesis homeobox.	0.845
BMP15	POF1B	ENSOCUP00000020965	ENSOCUP00000007613	TGF_BETA_2 domain-containing protein.	POF1B actin binding protein.	0.666
DIAPH2	POF1B	ENSOCUP00000006152	ENSOCUP00000007613	Diaphanous related formin 2.	POF1B actin binding protein.	0.590
ERICH6	LIMCH1	ENSOCUP00000007182	ENSOCUP00000013367	Glutamate rich 6.	LIM and calponin homology domains 1.	0.542
ERICH6	POF1B	ENSOCUP00000007182	ENSOCUP00000007613	Glutamate rich 6.	POF1B actin binding protein.	0.649
FIGLA	BMP15	ENSOCUP00000014858	ENSOCUP00000020965	Folliculogenesis specific bHLH transcription factor.	TGF_BETA_2 domain-containing protein.	0.855
FIGLA	NOBOX	ENSOCUP00000014858	ENSOCUP00000000887	Folliculogenesis specific bHLH transcription factor.	NOBOX oogenesis homeobox.	0.946
FIGLA	POF1B	ENSOCUP00000014858	ENSOCUP00000007613	Folliculogenesis specific bHLH transcription factor.	POF1B actin binding protein.	0.728
KIAA1191	POF1B	ENSOCUP00000042390	ENSOCUP00000007613	KIAA1191.	POF1B actin binding protein.	0.768
LIMCH1	ERICH6	ENSOCUP00000013367	ENSOCUP00000007182	LIM and calponin homology domains 1.	Glutamate rich 6.	0.542
LIMCH1	POF1B	ENSOCUP00000013367	ENSOCUP00000007613	LIM and calponin homology domains 1.	POF1B actin binding protein.	0.693
LIMCH1	TMOD1	ENSOCUP00000013367	ENSOCUP00000011899	LIM and calponin homology domains 1.	Tropomodulin 1.	0.476
LIMCH1	TMPO	ENSOCUP00000013367	ENSOCUP00000038289	LIM and calponin homology domains 1.	Thymopoietin.	0.517
NOBOX	BMP15	ENSOCUP00000000887	ENSOCUP00000020965	NOBOX oogenesis homeobox.	TGF_BETA_2 domain-containing protein.	0.845
NOBOX	FIGLA	ENSOCUP00000000887	ENSOCUP00000014858	NOBOX oogenesis homeobox.	Folliculogenesis specific bHLH transcription factor.	0.946
NOBOX	POF1B	ENSOCUP00000000887	ENSOCUP00000007613	NOBOX oogenesis homeobox.	POF1B actin binding protein.	0.710
POF1B	AMER2	ENSOCUP00000007613	ENSOCUP00000006574	POF1B actin binding protein.	APC membrane recruitment protein 2.	0.735
POF1B	BMP15	ENSOCUP00000007613	ENSOCUP00000020965	POF1B actin binding protein.	TGF_BETA_2 domain-containing protein.	0.666