Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADAT2Adenosine deaminase tRNA specific 2. (192 aa)    
Predicted Functional Partners:
RPUSD2
RNA pseudouridine synthase domain containing 2.
   
 0.782
RPUSD4
RNA pseudouridine synthase D4.
   
 0.731
CTU1
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
  
 
 0.718
TRMT6
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
   
  
 0.701
UPRT
Uracil phosphoribosyltransferase homolog.
   
 0.700
PUS7L
Pseudouridine synthase 7 like.
  
  
 0.692
BUD23
BUD23 rRNA methyltransferase and ribosome maturation factor.
  
  
 0.691
TYMS
Thymidylate synthetase.
  
 
 0.682
ENSOCUP00000042987
Thymidylat_synt domain-containing protein.
  
 
 0.682
TK1
Thymidine kinase.
    
 0.678
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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