| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAT2 | BUD23 | ENSOCUP00000007707 | ENSOCUP00000014860 | Adenosine deaminase tRNA specific 2. | BUD23 rRNA methyltransferase and ribosome maturation factor. | 0.691 |
| ADAT2 | CTU1 | ENSOCUP00000007707 | ENSOCUP00000026986 | Adenosine deaminase tRNA specific 2. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | 0.718 |
| ADAT2 | ENSOCUP00000042987 | ENSOCUP00000007707 | ENSOCUP00000042987 | Adenosine deaminase tRNA specific 2. | Thymidylat_synt domain-containing protein. | 0.682 |
| ADAT2 | PUS7L | ENSOCUP00000007707 | ENSOCUP00000003543 | Adenosine deaminase tRNA specific 2. | Pseudouridine synthase 7 like. | 0.692 |
| ADAT2 | RPUSD2 | ENSOCUP00000007707 | ENSOCUP00000013525 | Adenosine deaminase tRNA specific 2. | RNA pseudouridine synthase domain containing 2. | 0.782 |
| ADAT2 | RPUSD4 | ENSOCUP00000007707 | ENSOCUP00000014640 | Adenosine deaminase tRNA specific 2. | RNA pseudouridine synthase D4. | 0.731 |
| ADAT2 | TK1 | ENSOCUP00000007707 | ENSOCUP00000046611 | Adenosine deaminase tRNA specific 2. | Thymidine kinase. | 0.678 |
| ADAT2 | TRMT6 | ENSOCUP00000007707 | ENSOCUP00000018321 | Adenosine deaminase tRNA specific 2. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.701 |
| ADAT2 | TYMS | ENSOCUP00000007707 | ENSOCUP00000007483 | Adenosine deaminase tRNA specific 2. | Thymidylate synthetase. | 0.682 |
| ADAT2 | UPRT | ENSOCUP00000007707 | ENSOCUP00000015975 | Adenosine deaminase tRNA specific 2. | Uracil phosphoribosyltransferase homolog. | 0.700 |
| BUD23 | ADAT2 | ENSOCUP00000014860 | ENSOCUP00000007707 | BUD23 rRNA methyltransferase and ribosome maturation factor. | Adenosine deaminase tRNA specific 2. | 0.691 |
| BUD23 | CTU1 | ENSOCUP00000014860 | ENSOCUP00000026986 | BUD23 rRNA methyltransferase and ribosome maturation factor. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | 0.471 |
| BUD23 | PUS7L | ENSOCUP00000014860 | ENSOCUP00000003543 | BUD23 rRNA methyltransferase and ribosome maturation factor. | Pseudouridine synthase 7 like. | 0.442 |
| BUD23 | RPUSD2 | ENSOCUP00000014860 | ENSOCUP00000013525 | BUD23 rRNA methyltransferase and ribosome maturation factor. | RNA pseudouridine synthase domain containing 2. | 0.605 |
| BUD23 | RPUSD4 | ENSOCUP00000014860 | ENSOCUP00000014640 | BUD23 rRNA methyltransferase and ribosome maturation factor. | RNA pseudouridine synthase D4. | 0.491 |
| CTU1 | ADAT2 | ENSOCUP00000026986 | ENSOCUP00000007707 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | Adenosine deaminase tRNA specific 2. | 0.718 |
| CTU1 | BUD23 | ENSOCUP00000026986 | ENSOCUP00000014860 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | BUD23 rRNA methyltransferase and ribosome maturation factor. | 0.471 |
| CTU1 | PUS7L | ENSOCUP00000026986 | ENSOCUP00000003543 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | Pseudouridine synthase 7 like. | 0.614 |
| CTU1 | RPUSD2 | ENSOCUP00000026986 | ENSOCUP00000013525 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | RNA pseudouridine synthase domain containing 2. | 0.440 |
| CTU1 | TRMT6 | ENSOCUP00000026986 | ENSOCUP00000018321 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.538 |