MARCKSL1 protein (Oryctolagus cuniculus) - STRING interaction network

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MARCKSL1

MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). (189 aa)

Predicted Functional Partners:

MARCKS

0.898

PRKCE

0.851

PRKCD

0.851

RMI1

0.770

PRKCH

0.732

PRKCQ

0.712

MAPT

0.583

TNFAIP2

0.500

TDRD3

0.496

BASP1

0.492

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BASP1	MAPT	ENSOCUP00000032476	ENSOCUP00000030145	Brain abundant membrane attached signal protein 1.	Microtubule-associated protein.	0.583
BASP1	MARCKS	ENSOCUP00000032476	ENSOCUP00000006075	Brain abundant membrane attached signal protein 1.	Myristoylated alanine rich protein kinase C substrate.	0.706
BASP1	MARCKSL1	ENSOCUP00000032476	ENSOCUP00000007731	Brain abundant membrane attached signal protein 1.	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	0.492
MAPT	BASP1	ENSOCUP00000030145	ENSOCUP00000032476	Microtubule-associated protein.	Brain abundant membrane attached signal protein 1.	0.583
MAPT	MARCKSL1	ENSOCUP00000030145	ENSOCUP00000007731	Microtubule-associated protein.	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	0.583
MARCKS	BASP1	ENSOCUP00000006075	ENSOCUP00000032476	Myristoylated alanine rich protein kinase C substrate.	Brain abundant membrane attached signal protein 1.	0.706
MARCKS	MARCKSL1	ENSOCUP00000006075	ENSOCUP00000007731	Myristoylated alanine rich protein kinase C substrate.	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	0.898
MARCKS	PRKCD	ENSOCUP00000006075	ENSOCUP00000028837	Myristoylated alanine rich protein kinase C substrate.	Uncharacterized protein.	0.899
MARCKS	PRKCE	ENSOCUP00000006075	ENSOCUP00000011861	Myristoylated alanine rich protein kinase C substrate.	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...]	0.825
MARCKS	PRKCH	ENSOCUP00000006075	ENSOCUP00000013626	Myristoylated alanine rich protein kinase C substrate.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.750
MARCKS	PRKCQ	ENSOCUP00000006075	ENSOCUP00000008493	Myristoylated alanine rich protein kinase C substrate.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.746
MARCKSL1	BASP1	ENSOCUP00000007731	ENSOCUP00000032476	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Brain abundant membrane attached signal protein 1.	0.492
MARCKSL1	MAPT	ENSOCUP00000007731	ENSOCUP00000030145	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Microtubule-associated protein.	0.583
MARCKSL1	MARCKS	ENSOCUP00000007731	ENSOCUP00000006075	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Myristoylated alanine rich protein kinase C substrate.	0.898
MARCKSL1	PRKCD	ENSOCUP00000007731	ENSOCUP00000028837	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Uncharacterized protein.	0.851
MARCKSL1	PRKCE	ENSOCUP00000007731	ENSOCUP00000011861	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...]	0.851
MARCKSL1	PRKCH	ENSOCUP00000007731	ENSOCUP00000013626	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.732
MARCKSL1	PRKCQ	ENSOCUP00000007731	ENSOCUP00000008493	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.712
MARCKSL1	RMI1	ENSOCUP00000007731	ENSOCUP00000020169	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	RecQ mediated genome instability 1.	0.770
MARCKSL1	TDRD3	ENSOCUP00000007731	ENSOCUP00000012265	MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).	Tudor domain containing 3.	0.496

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