node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BASP1 | MARCKS | ENSOCUP00000032476 | ENSOCUP00000006075 | Brain abundant membrane attached signal protein 1. | Myristoylated alanine rich protein kinase C substrate. | 0.770 |
BASP1 | MARCKSL1 | ENSOCUP00000032476 | ENSOCUP00000007731 | Brain abundant membrane attached signal protein 1. | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). | 0.654 |
C18orf25 | MARCKSL1 | ENSOCUP00000008251 | ENSOCUP00000007731 | Chromosome 18 open reading frame 25. | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). | 0.450 |
CALM1 | CALM2 | ENSOCUP00000010025 | ENSOCUP00000048696 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Uncharacterized protein; Belongs to the calmodulin family. | 0.440 |
CALM1 | CALML5 | ENSOCUP00000010025 | ENSOCUP00000010863 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Calmodulin like 5. | 0.938 |
CALM1 | MARCKS | ENSOCUP00000010025 | ENSOCUP00000006075 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Myristoylated alanine rich protein kinase C substrate. | 0.755 |
CALM1 | MARCKSL1 | ENSOCUP00000010025 | ENSOCUP00000007731 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). | 0.579 |
CALM2 | CALM1 | ENSOCUP00000048696 | ENSOCUP00000010025 | Uncharacterized protein; Belongs to the calmodulin family. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 0.440 |
CALM2 | MARCKS | ENSOCUP00000048696 | ENSOCUP00000006075 | Uncharacterized protein; Belongs to the calmodulin family. | Myristoylated alanine rich protein kinase C substrate. | 0.851 |
CALM2 | MARCKSL1 | ENSOCUP00000048696 | ENSOCUP00000007731 | Uncharacterized protein; Belongs to the calmodulin family. | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). | 0.580 |
CALML5 | CALM1 | ENSOCUP00000010863 | ENSOCUP00000010025 | Calmodulin like 5. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 0.938 |
CALML5 | MARCKS | ENSOCUP00000010863 | ENSOCUP00000006075 | Calmodulin like 5. | Myristoylated alanine rich protein kinase C substrate. | 0.851 |
CALML5 | MARCKSL1 | ENSOCUP00000010863 | ENSOCUP00000007731 | Calmodulin like 5. | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). | 0.580 |
MARCKS | BASP1 | ENSOCUP00000006075 | ENSOCUP00000032476 | Myristoylated alanine rich protein kinase C substrate. | Brain abundant membrane attached signal protein 1. | 0.770 |
MARCKS | CALM1 | ENSOCUP00000006075 | ENSOCUP00000010025 | Myristoylated alanine rich protein kinase C substrate. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 0.755 |
MARCKS | CALM2 | ENSOCUP00000006075 | ENSOCUP00000048696 | Myristoylated alanine rich protein kinase C substrate. | Uncharacterized protein; Belongs to the calmodulin family. | 0.851 |
MARCKS | CALML5 | ENSOCUP00000006075 | ENSOCUP00000010863 | Myristoylated alanine rich protein kinase C substrate. | Calmodulin like 5. | 0.851 |
MARCKS | MARCKSL1 | ENSOCUP00000006075 | ENSOCUP00000007731 | Myristoylated alanine rich protein kinase C substrate. | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (By similarity). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable). | 0.933 |
MARCKS | PALM | ENSOCUP00000006075 | ENSOCUP00000020660 | Myristoylated alanine rich protein kinase C substrate. | Uncharacterized protein. | 0.403 |
MARCKS | PRKCE | ENSOCUP00000006075 | ENSOCUP00000011861 | Myristoylated alanine rich protein kinase C substrate. | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] | 0.922 |