STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (732 aa)    
Predicted Functional Partners:
ANGPT1
Angiopoietin 1.
   
 0.990
ANGPT2
Angiopoietin 2.
   
 0.977
ENSOCUP00000035160
Ig domain-containing protein.
 
     0.924
ANGPT4
Angiopoietin 4.
   
 0.883
PECAM1
Platelet and endothelial cell adhesion molecule 1.
   
 0.792
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.768
NOS3
Nitric oxide synthase; Produces nitric oxide (NO).
   
  
 0.752
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.708
ANGPTL7
Angiopoietin like 7.
   
 0.668
VWF
Von Willebrand factor.
   
  
 0.668
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.