EBF1 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EBF1

EBF transcription factor 1. (591 aa)

Predicted Functional Partners:

PAX5

0.841

ZNF423

0.729

EBF2

0.729

LHX2

0.691

ZNF521

0.673

IKZF1

0.663

CEBPB

0.617

CEBPA

0.605

PPARG

0.594

ISL1

0.586

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPA	CEBPB	ENSOCUP00000022073	ENSOCUP00000016553	CCAAT enhancer binding protein alpha.	CCAAT enhancer binding protein beta.	0.891
CEBPA	EBF1	ENSOCUP00000022073	ENSOCUP00000007763	CCAAT enhancer binding protein alpha.	EBF transcription factor 1.	0.605
CEBPA	EBF2	ENSOCUP00000022073	ENSOCUP00000045602	CCAAT enhancer binding protein alpha.	EBF transcription factor 2.	0.435
CEBPA	IKZF1	ENSOCUP00000022073	ENSOCUP00000012401	CCAAT enhancer binding protein alpha.	IKAROS family zinc finger 1.	0.448
CEBPA	PAX5	ENSOCUP00000022073	ENSOCUP00000010574	CCAAT enhancer binding protein alpha.	Paired box 5.	0.404
CEBPA	PPARG	ENSOCUP00000022073	ENSOCUP00000043929	CCAAT enhancer binding protein alpha.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.928
CEBPB	CEBPA	ENSOCUP00000016553	ENSOCUP00000022073	CCAAT enhancer binding protein beta.	CCAAT enhancer binding protein alpha.	0.891
CEBPB	EBF1	ENSOCUP00000016553	ENSOCUP00000007763	CCAAT enhancer binding protein beta.	EBF transcription factor 1.	0.617
CEBPB	EBF2	ENSOCUP00000016553	ENSOCUP00000045602	CCAAT enhancer binding protein beta.	EBF transcription factor 2.	0.532
CEBPB	PPARG	ENSOCUP00000016553	ENSOCUP00000043929	CCAAT enhancer binding protein beta.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.957
EBF1	CEBPA	ENSOCUP00000007763	ENSOCUP00000022073	EBF transcription factor 1.	CCAAT enhancer binding protein alpha.	0.605
EBF1	CEBPB	ENSOCUP00000007763	ENSOCUP00000016553	EBF transcription factor 1.	CCAAT enhancer binding protein beta.	0.617
EBF1	EBF2	ENSOCUP00000007763	ENSOCUP00000045602	EBF transcription factor 1.	EBF transcription factor 2.	0.729
EBF1	IKZF1	ENSOCUP00000007763	ENSOCUP00000012401	EBF transcription factor 1.	IKAROS family zinc finger 1.	0.663
EBF1	ISL1	ENSOCUP00000007763	ENSOCUP00000020036	EBF transcription factor 1.	ISL LIM homeobox 1.	0.586
EBF1	LHX2	ENSOCUP00000007763	ENSOCUP00000006701	EBF transcription factor 1.	LIM homeobox 2.	0.691
EBF1	PAX5	ENSOCUP00000007763	ENSOCUP00000010574	EBF transcription factor 1.	Paired box 5.	0.841
EBF1	PPARG	ENSOCUP00000007763	ENSOCUP00000043929	EBF transcription factor 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.594
EBF1	ZNF423	ENSOCUP00000007763	ENSOCUP00000032422	EBF transcription factor 1.	Zinc finger protein 423.	0.729
EBF1	ZNF521	ENSOCUP00000007763	ENSOCUP00000033821	EBF transcription factor 1.	Zinc finger protein 521.	0.673