OGN protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OGN

Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2. (298 aa)

Predicted Functional Partners:

LUM

0.862

ASPN

0.853

KERA

0.822

OMD

0.805

BGN

0.792

ADGRL1

0.743

ADGRL3

0.743

ADGRL2

0.743

FMOD

0.742

ACAN

0.741

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	ASPN	ENSOCUP00000024918	ENSOCUP00000024373	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Asporin.	0.717
ACAN	BGN	ENSOCUP00000024918	ENSOCUP00000026470	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Biglycan; May be involved in collagen fiber assembly.	0.948
ACAN	FMOD	ENSOCUP00000024918	ENSOCUP00000007954	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.	0.947
ACAN	KERA	ENSOCUP00000024918	ENSOCUP00000011522	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Keratocan.	0.771
ACAN	LUM	ENSOCUP00000024918	ENSOCUP00000004852	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Lumican.	0.893
ACAN	OGN	ENSOCUP00000024918	ENSOCUP00000007778	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2.	0.741
ACAN	OMD	ENSOCUP00000024918	ENSOCUP00000013912	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Osteomodulin.	0.546
ADGRL1	ASPN	ENSOCUP00000023951	ENSOCUP00000024373	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Asporin.	0.743
ADGRL1	BGN	ENSOCUP00000023951	ENSOCUP00000026470	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Biglycan; May be involved in collagen fiber assembly.	0.743
ADGRL1	FMOD	ENSOCUP00000023951	ENSOCUP00000007954	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.	0.743
ADGRL1	KERA	ENSOCUP00000023951	ENSOCUP00000011522	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Keratocan.	0.743
ADGRL1	LUM	ENSOCUP00000023951	ENSOCUP00000004852	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Lumican.	0.743
ADGRL1	OGN	ENSOCUP00000023951	ENSOCUP00000007778	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2.	0.743
ADGRL1	OMD	ENSOCUP00000023951	ENSOCUP00000013912	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Osteomodulin.	0.743
ADGRL2	ASPN	ENSOCUP00000044036	ENSOCUP00000024373	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Asporin.	0.743
ADGRL2	BGN	ENSOCUP00000044036	ENSOCUP00000026470	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Biglycan; May be involved in collagen fiber assembly.	0.743
ADGRL2	FMOD	ENSOCUP00000044036	ENSOCUP00000007954	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.	0.743
ADGRL2	KERA	ENSOCUP00000044036	ENSOCUP00000011522	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Keratocan.	0.743
ADGRL2	LUM	ENSOCUP00000044036	ENSOCUP00000004852	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Lumican.	0.743
ADGRL2	OGN	ENSOCUP00000044036	ENSOCUP00000007778	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2.	0.743