STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRG1FSHD region gene 1. (258 aa)    
Predicted Functional Partners:
CWC22
CWC22 spliceosome associated protein homolog.
   
   0.982
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
 
      0.801
PRPF8
Pre-mRNA processing factor 8.
    
 
 0.792
PRPF19
Pre-mRNA processing factor 19.
    
   0.749
SNRPF
Small nuclear ribonucleoprotein polypeptide F.
   
 
 0.713
OR4C5
Olfactory receptor.
      
 0.697
SNRPD1
Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
    
 
 0.666
SYF2
SYF2 pre-mRNA splicing factor.
   
   0.656
BCAS2
BCAS2 pre-mRNA processing factor.
   
 
 0.649
CWC15
CWC15 spliceosome associated protein homolog.
   
 
 0.646
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.