Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CNKSR3CNKSR family member 3. (555 aa)    
Predicted Functional Partners:
IPCEF1
Interaction protein for cytohesin exchange factors 1.
 
 
 
 0.886
CCDC175
Coiled-coil domain containing 175.
      
 0.825
CLVS2
Clavesin 2.
   
  
 0.717
SAMD12
Sterile alpha motif domain containing 12.
    
 0.666
KSR2
Kinase suppressor of ras 2.
    
 0.652
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.649
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.649
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.649
KSR1
Kinase suppressor of ras 1.
    
 0.645
NISCH
Nischarin.
    
   0.642
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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