Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (622 aa)    
Predicted Functional Partners:
SIX1
SIX homeobox 1.
   
 0.994
SIX2
SIX homeobox 2.
   
 0.976
PAX2
Paired box 2.
    
 0.929
PAX8
Paired box 8.
    
 0.842
DACH1
Dachshund family transcription factor 1.
    
 
 0.795
SALL1
Uncharacterized protein.
   
 
 0.786
DACH2
Dachshund family transcription factor 2.
    
 
 0.682
SIX6
SIX homeobox 6.
   
 0.663
HOXD11
Homeobox domain-containing protein.
    
 0.663
GDNF
Glial cell derived neurotrophic factor.
     
 0.661
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.