Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHR | AIP | ENSOCUP00000042767 | ENSOCUP00000044792 | Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] | Peptidylprolyl isomerase. | 0.991 |
| AHR | G1SWK6_RABIT | ENSOCUP00000042767 | ENSOCUP00000007873 | Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] | HATPase_c domain-containing protein. | 0.782 |
| AHR | PTGES3 | ENSOCUP00000042767 | ENSOCUP00000029851 | Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.851 |
| AIP | AHR | ENSOCUP00000044792 | ENSOCUP00000042767 | Peptidylprolyl isomerase. | Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] | 0.991 |
| AIP | G1SWK6_RABIT | ENSOCUP00000044792 | ENSOCUP00000007873 | Peptidylprolyl isomerase. | HATPase_c domain-containing protein. | 0.805 |
| AIP | PTGES3 | ENSOCUP00000044792 | ENSOCUP00000029851 | Peptidylprolyl isomerase. | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.904 |
| CDC37L1 | FKBP5 | ENSOCUP00000003006 | ENSOCUP00000046356 | Cell division cycle 37 like 1. | Peptidylprolyl isomerase. | 0.462 |
| CDC37L1 | G1SWK6_RABIT | ENSOCUP00000003006 | ENSOCUP00000007873 | Cell division cycle 37 like 1. | HATPase_c domain-containing protein. | 0.854 |
| CDC37L1 | PPP5C | ENSOCUP00000003006 | ENSOCUP00000018147 | Cell division cycle 37 like 1. | Serine/threonine-protein phosphatase 5; Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Pa [...] | 0.920 |
| CDC37L1 | PTGES3 | ENSOCUP00000003006 | ENSOCUP00000029851 | Cell division cycle 37 like 1. | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.709 |
| CDC37L1 | STIP1 | ENSOCUP00000003006 | ENSOCUP00000029749 | Cell division cycle 37 like 1. | Stress induced phosphoprotein 1. | 0.917 |
| FKBP5 | CDC37L1 | ENSOCUP00000046356 | ENSOCUP00000003006 | Peptidylprolyl isomerase. | Cell division cycle 37 like 1. | 0.462 |
| FKBP5 | G1SWK6_RABIT | ENSOCUP00000046356 | ENSOCUP00000007873 | Peptidylprolyl isomerase. | HATPase_c domain-containing protein. | 0.801 |
| FKBP5 | MTOR | ENSOCUP00000046356 | ENSOCUP00000011253 | Peptidylprolyl isomerase. | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.808 |
| FKBP5 | NR3C1 | ENSOCUP00000046356 | ENSOCUP00000046838 | Peptidylprolyl isomerase. | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] | 0.966 |
| FKBP5 | PPP5C | ENSOCUP00000046356 | ENSOCUP00000018147 | Peptidylprolyl isomerase. | Serine/threonine-protein phosphatase 5; Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Pa [...] | 0.588 |
| FKBP5 | PTGES3 | ENSOCUP00000046356 | ENSOCUP00000029851 | Peptidylprolyl isomerase. | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.957 |
| FKBP5 | STIP1 | ENSOCUP00000046356 | ENSOCUP00000029749 | Peptidylprolyl isomerase. | Stress induced phosphoprotein 1. | 0.810 |
| G1SWK6_RABIT | AHR | ENSOCUP00000007873 | ENSOCUP00000042767 | HATPase_c domain-containing protein. | Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] | 0.782 |
| G1SWK6_RABIT | AIP | ENSOCUP00000007873 | ENSOCUP00000044792 | HATPase_c domain-containing protein. | Peptidylprolyl isomerase. | 0.805 |
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