SLC1A5 protein (Oryctolagus cuniculus) - STRING interaction network

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SLC1A5

Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. (540 aa)

Predicted Functional Partners:

SLC3A2

0.893

SLC1A7

0.888

SLC6A14

0.865

SLC7A1

0.833

SLC38A1

0.828

GLS

0.827

SLC7A8

0.819

SLC38A2

0.811

GLS2

0.774

NUDCD1

0.745

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLS	GLS2	ENSOCUP00000002118	ENSOCUP00000035787	Glutaminase.	Glutaminase 2.	0.964
GLS	SLC1A5	ENSOCUP00000002118	ENSOCUP00000007892	Glutaminase.	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	0.827
GLS	SLC1A7	ENSOCUP00000002118	ENSOCUP00000002220	Glutaminase.	Amino acid transporter.	0.593
GLS	SLC38A1	ENSOCUP00000002118	ENSOCUP00000004477	Glutaminase.	Solute carrier family 38 member 1.	0.461
GLS	SLC38A2	ENSOCUP00000002118	ENSOCUP00000029933	Glutaminase.	Solute carrier family 38 member 2.	0.456
GLS2	GLS	ENSOCUP00000035787	ENSOCUP00000002118	Glutaminase 2.	Glutaminase.	0.964
GLS2	SLC1A5	ENSOCUP00000035787	ENSOCUP00000007892	Glutaminase 2.	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	0.774
GLS2	SLC38A1	ENSOCUP00000035787	ENSOCUP00000004477	Glutaminase 2.	Solute carrier family 38 member 1.	0.504
GLS2	SLC3A2	ENSOCUP00000035787	ENSOCUP00000001148	Glutaminase 2.	4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...]	0.462
NUDCD1	SLC1A5	ENSOCUP00000004041	ENSOCUP00000007892	NudC domain containing 1.	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	0.745
SLC1A5	GLS	ENSOCUP00000007892	ENSOCUP00000002118	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Glutaminase.	0.827
SLC1A5	GLS2	ENSOCUP00000007892	ENSOCUP00000035787	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Glutaminase 2.	0.774
SLC1A5	NUDCD1	ENSOCUP00000007892	ENSOCUP00000004041	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	NudC domain containing 1.	0.745
SLC1A5	SLC1A7	ENSOCUP00000007892	ENSOCUP00000002220	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Amino acid transporter.	0.888
SLC1A5	SLC38A1	ENSOCUP00000007892	ENSOCUP00000004477	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Solute carrier family 38 member 1.	0.828
SLC1A5	SLC38A2	ENSOCUP00000007892	ENSOCUP00000029933	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Solute carrier family 38 member 2.	0.811
SLC1A5	SLC3A2	ENSOCUP00000007892	ENSOCUP00000001148	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...]	0.893
SLC1A5	SLC6A14	ENSOCUP00000007892	ENSOCUP00000012915	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.865
SLC1A5	SLC7A1	ENSOCUP00000007892	ENSOCUP00000047781	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Solute carrier family 7 member 1.	0.833
SLC1A5	SLC7A8	ENSOCUP00000007892	ENSOCUP00000019754	Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.	Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administe [...]	0.819

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