RFWD3 protein (Oryctolagus cuniculus) - STRING interaction network

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000042618	RFWD3	ENSOCUP00000042618	ENSOCUP00000007899	annotation not available	Ring finger and WD repeat domain 3.	0.767
ENSOCUP00000042618	RPA1	ENSOCUP00000042618	ENSOCUP00000042935	annotation not available	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.792
ENSOCUP00000042618	RPA2	ENSOCUP00000042618	ENSOCUP00000013917	annotation not available	Replication protein A2.	0.549
ENSOCUP00000042618	RPA3	ENSOCUP00000042618	ENSOCUP00000000408	annotation not available	Replication protein A3.	0.763
ENSOCUP00000042618	SMARCAL1	ENSOCUP00000042618	ENSOCUP00000008523	annotation not available	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.821
ENSOCUP00000042618	TIMELESS	ENSOCUP00000042618	ENSOCUP00000010377	annotation not available	Timeless circadian regulator.	0.806
ENSOCUP00000042618	WRN	ENSOCUP00000042618	ENSOCUP00000010872	annotation not available	WRN RecQ like helicase.	0.669
ENSOCUP00000042618	ZRANB3	ENSOCUP00000042618	ENSOCUP00000038477	annotation not available	Zinc finger RANBP2-type containing 3.	0.659
HMCES	PRIMPOL	ENSOCUP00000005176	ENSOCUP00000003383	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Uncharacterized protein.	0.467
HMCES	RFWD3	ENSOCUP00000005176	ENSOCUP00000007899	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Ring finger and WD repeat domain 3.	0.713
HMCES	RPA2	ENSOCUP00000005176	ENSOCUP00000013917	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Replication protein A2.	0.552
HMCES	SMARCAL1	ENSOCUP00000005176	ENSOCUP00000008523	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.495
PRIMPOL	HMCES	ENSOCUP00000003383	ENSOCUP00000005176	Uncharacterized protein.	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	0.467
PRIMPOL	RFWD3	ENSOCUP00000003383	ENSOCUP00000007899	Uncharacterized protein.	Ring finger and WD repeat domain 3.	0.921
PRIMPOL	RPA1	ENSOCUP00000003383	ENSOCUP00000042935	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.929
PRIMPOL	RPA2	ENSOCUP00000003383	ENSOCUP00000013917	Uncharacterized protein.	Replication protein A2.	0.787
PRIMPOL	RPA3	ENSOCUP00000003383	ENSOCUP00000000408	Uncharacterized protein.	Replication protein A3.	0.945
PRIMPOL	SMARCAL1	ENSOCUP00000003383	ENSOCUP00000008523	Uncharacterized protein.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.984
PRIMPOL	TIMELESS	ENSOCUP00000003383	ENSOCUP00000010377	Uncharacterized protein.	Timeless circadian regulator.	0.948
PRIMPOL	WRN	ENSOCUP00000003383	ENSOCUP00000010872	Uncharacterized protein.	WRN RecQ like helicase.	0.780