Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRX2Iroquois homeobox 2. (335 aa)    
Predicted Functional Partners:
IRX1
Iroquois homeobox 1.
   
  
0.719
HHEX
Homeobox domain-containing protein.
   
 
 0.655
HOXD12
Homeobox D12.
    
 
 0.539
ISL1
ISL LIM homeobox 1.
   
 
 0.536
TSHZ1
Teashirt zinc finger homeobox 1.
   
 0.526
DLX1
Distal-less homeobox 1.
   
 
 0.520
MAFB
MAF bZIP transcription factor B.
      
 0.512
NKX6-1
NK6 homeobox 1.
      
 0.484
PAX4
Paired box 4.
    
 
 0.479
PAX6
Uncharacterized protein.
    
 
 0.474
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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