Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VIMVimentin; Belongs to the intermediate filament family. (466 aa)    
Predicted Functional Partners:
DES
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
  0.981
NEFL
Neurofilament light; Belongs to the intermediate filament family.
   
 
 0.936
NES
Nestin; Belongs to the intermediate filament family.
   
 
0.935
NEFM
Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
   
 
 0.930
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  0.902
SNAI1
Snail family transcriptional repressor 1.
   
  
 0.869
GAN
Gigaxonin.
    
 
 0.854
PRPH
Peripherin; Belongs to the intermediate filament family.
   
   0.850
ZEB1
Zinc finger E-box binding homeobox 1.
   
 
 0.845
DSP
Desmoplakin.
   
 0.844
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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