Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENC1Ectodermal-neural cortex 1. (589 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.944
KLHL25
Kelch like family member 25.
    
   0.917
NFE2L2
Nuclear factor, erythroid 2 like 2.
    
 0.771
NUDCD3
CS domain-containing protein.
    
   0.767
KLHL13
Kelch like family member 13.
  
 
0.592
RB1
RB transcriptional corepressor 1.
    
 
 0.575
KLHL9
Kelch like family member 9.
  
 
0.574
PLAGL2
PLAG1 like zinc finger 2.
    
 0.554
HEXB
Beta-hexosaminidase.
      
 0.551
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.530
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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