OR4E2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

OR4E2

Olfactory receptor. (308 aa)

Predicted Functional Partners:

GNAL

0.669

ARRB1

0.649

ENSOCUP00000035103

0.636

PRKACB

0.622

GNB4

0.497

GNB1

0.497

GRK3

0.480

ENSOCUP00000039917

0.480

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB1	ENSOCUP00000039917	ENSOCUP00000019641	ENSOCUP00000039917	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	RGS domain-containing protein.	0.893
ARRB1	GNB1	ENSOCUP00000019641	ENSOCUP00000008676	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein subunit beta 1.	0.691
ARRB1	GNB4	ENSOCUP00000019641	ENSOCUP00000000803	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein subunit beta 4.	0.691
ARRB1	GRK3	ENSOCUP00000019641	ENSOCUP00000022116	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.918
ARRB1	OR4E2	ENSOCUP00000019641	ENSOCUP00000007969	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Olfactory receptor.	0.649
ARRB1	PRKACB	ENSOCUP00000019641	ENSOCUP00000043583	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.594
ENSOCUP00000035103	ENSOCUP00000039917	ENSOCUP00000035103	ENSOCUP00000039917	G protein gamma domain-containing protein.	RGS domain-containing protein.	0.424
ENSOCUP00000035103	GNAL	ENSOCUP00000035103	ENSOCUP00000004556	G protein gamma domain-containing protein.	G protein subunit alpha L.	0.972
ENSOCUP00000035103	GNB1	ENSOCUP00000035103	ENSOCUP00000008676	G protein gamma domain-containing protein.	G protein subunit beta 1.	0.961
ENSOCUP00000035103	GNB4	ENSOCUP00000035103	ENSOCUP00000000803	G protein gamma domain-containing protein.	G protein subunit beta 4.	0.961
ENSOCUP00000035103	GRK3	ENSOCUP00000035103	ENSOCUP00000022116	G protein gamma domain-containing protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.424
ENSOCUP00000035103	OR4E2	ENSOCUP00000035103	ENSOCUP00000007969	G protein gamma domain-containing protein.	Olfactory receptor.	0.636
ENSOCUP00000035103	PRKACB	ENSOCUP00000035103	ENSOCUP00000043583	G protein gamma domain-containing protein.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.863
ENSOCUP00000039917	ARRB1	ENSOCUP00000039917	ENSOCUP00000019641	RGS domain-containing protein.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.893
ENSOCUP00000039917	ENSOCUP00000035103	ENSOCUP00000039917	ENSOCUP00000035103	RGS domain-containing protein.	G protein gamma domain-containing protein.	0.424
ENSOCUP00000039917	GNB1	ENSOCUP00000039917	ENSOCUP00000008676	RGS domain-containing protein.	G protein subunit beta 1.	0.716
ENSOCUP00000039917	GNB4	ENSOCUP00000039917	ENSOCUP00000000803	RGS domain-containing protein.	G protein subunit beta 4.	0.716
ENSOCUP00000039917	OR4E2	ENSOCUP00000039917	ENSOCUP00000007969	RGS domain-containing protein.	Olfactory receptor.	0.480
GNAL	ENSOCUP00000035103	ENSOCUP00000004556	ENSOCUP00000035103	G protein subunit alpha L.	G protein gamma domain-containing protein.	0.972
GNAL	GNB1	ENSOCUP00000004556	ENSOCUP00000008676	G protein subunit alpha L.	G protein subunit beta 1.	0.970