AP3S1 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AP3S1

Adaptor related protein complex 3 subunit sigma 1. (193 aa)

Predicted Functional Partners:

AP3B1

0.980

AP3B2

0.977

AP3M1

0.969

AP3M2

0.965

GAK

0.958

AP3S2

0.900

LOC100354898

0.883

LOC100341006

0.874

AP1G2

0.794

AP1G1

0.794

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1G1	AP1G2	ENSOCUP00000031161	ENSOCUP00000006678	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.904
AP1G1	AP3B1	ENSOCUP00000031161	ENSOCUP00000045044	AP-1 complex subunit gamma.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.875
AP1G1	AP3B2	ENSOCUP00000031161	ENSOCUP00000005580	AP-1 complex subunit gamma.	AP-3 complex subunit beta.	0.875
AP1G1	AP3M1	ENSOCUP00000031161	ENSOCUP00000008566	AP-1 complex subunit gamma.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.860
AP1G1	AP3M2	ENSOCUP00000031161	ENSOCUP00000029436	AP-1 complex subunit gamma.	AP-3 complex subunit mu-2.	0.762
AP1G1	AP3S1	ENSOCUP00000031161	ENSOCUP00000008005	AP-1 complex subunit gamma.	Adaptor related protein complex 3 subunit sigma 1.	0.794
AP1G1	AP3S2	ENSOCUP00000031161	ENSOCUP00000040005	AP-1 complex subunit gamma.	Adaptor related protein complex 3 subunit sigma 2.	0.794
AP1G1	GAK	ENSOCUP00000031161	ENSOCUP00000002563	AP-1 complex subunit gamma.	Cyclin G associated kinase.	0.980
AP1G2	AP1G1	ENSOCUP00000006678	ENSOCUP00000031161	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.904
AP1G2	AP3B1	ENSOCUP00000006678	ENSOCUP00000045044	AP-1 complex subunit gamma.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.876
AP1G2	AP3B2	ENSOCUP00000006678	ENSOCUP00000005580	AP-1 complex subunit gamma.	AP-3 complex subunit beta.	0.877
AP1G2	AP3M1	ENSOCUP00000006678	ENSOCUP00000008566	AP-1 complex subunit gamma.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.762
AP1G2	AP3M2	ENSOCUP00000006678	ENSOCUP00000029436	AP-1 complex subunit gamma.	AP-3 complex subunit mu-2.	0.882
AP1G2	AP3S1	ENSOCUP00000006678	ENSOCUP00000008005	AP-1 complex subunit gamma.	Adaptor related protein complex 3 subunit sigma 1.	0.794
AP1G2	AP3S2	ENSOCUP00000006678	ENSOCUP00000040005	AP-1 complex subunit gamma.	Adaptor related protein complex 3 subunit sigma 2.	0.794
AP1G2	GAK	ENSOCUP00000006678	ENSOCUP00000002563	AP-1 complex subunit gamma.	Cyclin G associated kinase.	0.980
AP3B1	AP1G1	ENSOCUP00000045044	ENSOCUP00000031161	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-1 complex subunit gamma.	0.875
AP3B1	AP1G2	ENSOCUP00000045044	ENSOCUP00000006678	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-1 complex subunit gamma.	0.876
AP3B1	AP3B2	ENSOCUP00000045044	ENSOCUP00000005580	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit beta.	0.903
AP3B1	AP3M1	ENSOCUP00000045044	ENSOCUP00000008566	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.991