STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (1058 aa)    
Predicted Functional Partners:
DLST
Dihydrolipoamide S-succinyltransferase.
 0.999
DLD
Dihydrolipoyl dehydrogenase.
  
 0.981
GCDH
Glutaryl-CoA dehydrogenase.
   
 
 0.964
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
 
 0.941
AADAT
Aminoadipate aminotransferase.
   
 
 0.937
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.903
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.903
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.903
LOC100341293
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.903
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.868
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.