SSTR2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

SSTR2

Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (366 aa)

Predicted Functional Partners:

SST

0.999

GNAI1

0.950

GNAI3

0.950

CORT

0.940

SSTR1

0.936

GNAI2

0.936

NPY

0.794

GHRL

0.790

EDN1

0.712

EDN3

0.699

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CORT	NPY	ENSOCUP00000020417	ENSOCUP00000009261	Somatostatin domain-containing protein.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.582
CORT	SST	ENSOCUP00000020417	ENSOCUP00000006540	Somatostatin domain-containing protein.	Somatostatin.	0.980
CORT	SSTR1	ENSOCUP00000020417	ENSOCUP00000018502	Somatostatin domain-containing protein.	Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.960
CORT	SSTR2	ENSOCUP00000020417	ENSOCUP00000008063	Somatostatin domain-containing protein.	Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.940
EDN1	EDN3	ENSOCUP00000011526	ENSOCUP00000046269	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	0.965
EDN1	GHRL	ENSOCUP00000011526	ENSOCUP00000029787	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Uncharacterized protein.	0.467
EDN1	GNAI1	ENSOCUP00000011526	ENSOCUP00000000882	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	G protein subunit alpha i1.	0.403
EDN1	NPY	ENSOCUP00000011526	ENSOCUP00000009261	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.426
EDN1	SSTR1	ENSOCUP00000011526	ENSOCUP00000018502	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.705
EDN1	SSTR2	ENSOCUP00000011526	ENSOCUP00000008063	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.712
EDN3	EDN1	ENSOCUP00000046269	ENSOCUP00000011526	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.965
EDN3	SSTR1	ENSOCUP00000046269	ENSOCUP00000018502	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.720
EDN3	SSTR2	ENSOCUP00000046269	ENSOCUP00000008063	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.699
GHRL	EDN1	ENSOCUP00000029787	ENSOCUP00000011526	Uncharacterized protein.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.467
GHRL	NPY	ENSOCUP00000029787	ENSOCUP00000009261	Uncharacterized protein.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.933
GHRL	SST	ENSOCUP00000029787	ENSOCUP00000006540	Uncharacterized protein.	Somatostatin.	0.887
GHRL	SSTR1	ENSOCUP00000029787	ENSOCUP00000018502	Uncharacterized protein.	Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.740
GHRL	SSTR2	ENSOCUP00000029787	ENSOCUP00000008063	Uncharacterized protein.	Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.790
GNAI1	EDN1	ENSOCUP00000000882	ENSOCUP00000011526	G protein subunit alpha i1.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.403
GNAI1	GNAI2	ENSOCUP00000000882	ENSOCUP00000019624	G protein subunit alpha i1.	G protein subunit alpha i2.	0.973