MAML3 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MAML3

Mastermind like transcriptional coactivator 3. (1124 aa)

Predicted Functional Partners:

RBPJ

0.998

NOTCH2

0.973

NOTCH4

0.946

MAML2

0.922

MAML1

0.910

EP300

0.838

CREBBP

0.836

JAG1

0.831

DLL1

0.764

DLL3

0.748

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSOCUP00000003854	ENSOCUP00000009840	CREB binding protein.	E1A binding protein p300.	0.998
CREBBP	MAML1	ENSOCUP00000003854	ENSOCUP00000012980	CREB binding protein.	Mastermind like transcriptional coactivator 1.	0.941
CREBBP	MAML2	ENSOCUP00000003854	ENSOCUP00000009308	CREB binding protein.	Mastermind like transcriptional coactivator 2.	0.924
CREBBP	MAML3	ENSOCUP00000003854	ENSOCUP00000008089	CREB binding protein.	Mastermind like transcriptional coactivator 3.	0.836
CREBBP	NOTCH2	ENSOCUP00000003854	ENSOCUP00000035735	CREB binding protein.	Notch receptor 2.	0.613
CREBBP	NOTCH4	ENSOCUP00000003854	ENSOCUP00000014145	CREB binding protein.	Uncharacterized protein.	0.683
CREBBP	RBPJ	ENSOCUP00000003854	ENSOCUP00000030848	CREB binding protein.	Recombination signal binding protein for immunoglobulin kappa J region.	0.965
DLL1	DLL3	ENSOCUP00000041831	ENSOCUP00000006267	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.925
DLL1	JAG1	ENSOCUP00000041831	ENSOCUP00000002511	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.682
DLL1	MAML1	ENSOCUP00000041831	ENSOCUP00000012980	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.798
DLL1	MAML2	ENSOCUP00000041831	ENSOCUP00000009308	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 2.	0.789
DLL1	MAML3	ENSOCUP00000041831	ENSOCUP00000008089	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 3.	0.764
DLL1	NOTCH2	ENSOCUP00000041831	ENSOCUP00000035735	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.995
DLL1	NOTCH4	ENSOCUP00000041831	ENSOCUP00000014145	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.996
DLL1	RBPJ	ENSOCUP00000041831	ENSOCUP00000030848	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region.	0.892
DLL3	DLL1	ENSOCUP00000006267	ENSOCUP00000041831	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.925
DLL3	MAML1	ENSOCUP00000006267	ENSOCUP00000012980	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 1.	0.750
DLL3	MAML2	ENSOCUP00000006267	ENSOCUP00000009308	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 2.	0.750
DLL3	MAML3	ENSOCUP00000006267	ENSOCUP00000008089	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 3.	0.748
DLL3	NOTCH2	ENSOCUP00000006267	ENSOCUP00000035735	Delta like canonical Notch ligand 3.	Notch receptor 2.	0.992