Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAML3Mastermind like transcriptional coactivator 3. (1124 aa)    
Predicted Functional Partners:
NOTCH2
Notch receptor 2.
   
 0.956
NOTCH4
Uncharacterized protein.
    
 0.954
NOTCH3
Notch receptor 3.
    
 0.954
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.942
ENSOCUP00000036101
Uncharacterized protein.
   
 0.902
MAML2
Mastermind like transcriptional coactivator 2.
     
 0.889
EP300
E1A binding protein p300.
    
 0.865
CREBBP
CREB binding protein.
    
 0.860
MAML1
Mastermind like transcriptional coactivator 1.
   
 
 0.859
KAT2A
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
     
 0.853
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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