Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HNRNPUL2Uncharacterized protein. (765 aa)    
Predicted Functional Partners:
RALY
RALY heterogeneous nuclear ribonucleoprotein.
   
 0.824
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B.
   
 0.822
HNRNPD
Heterogeneous nuclear ribonucleoprotein D.
   
 0.816
HNRNPK
Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]
   
 0.811
HNRNPL
Heterogeneous nuclear ribonucleoprotein L; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.760
AK3
GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
    
   0.759
ENSOCUP00000032104
ADK_lid domain-containing protein; Belongs to the adenylate kinase family.
    
   0.759
SRSF9
Serine and arginine rich splicing factor 9.
   
 0.755
LOC100344653
Uncharacterized protein.
   
 0.754
ENSOCUP00000028099
ROKNT domain-containing protein.
   
 0.754
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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