STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (842 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.990
PDS5A
PDS5 cohesin associated factor A.
   
 0.930
WAPL
WAPL cohesin release factor.
   
 
 0.923
PDS5B
PDS5 cohesin associated factor B.
   
 0.905
RAD21
RAD21 cohesin complex component.
   
 0.901
AANAT
Aralkylamine N-acetyltransferase.
   
  
 0.837
REC8
REC8 meiotic recombination protein.
   
 0.826
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.807
SMC1A
SMC hinge domain-containing protein.
   
 0.797
MAU2
MAU2 sister chromatid cohesion factor.
      
 0.791
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.