Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
    
 0.989
SPTSSA
Uncharacterized protein.
    
 0.967
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
    
 0.956
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
    
 0.956
ORMDL1
Uncharacterized protein.
   
    0.909
ORMDL2
ORM1-like protein; Negative regulator of sphingolipid synthesis.
   
    0.908
ORM1
Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction.
      
 0.797
ZPBP2
Zona pellucida binding protein 2.
      
 0.734
LRRC3C
Leucine rich repeat containing 3C.
      
 0.660
STIMATE
Uncharacterized protein.
   
 
 0.605
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (58%) [HD]