Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
GSDMAGasdermin A. (445 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
 
 
 0.796
TGM5
Transglutaminase 5.
   
  
 0.711
CASP14
Caspase 14; Belongs to the peptidase C14A family.
  
  
 0.629
GSDME
Gasdermin E.
      
 0.607
FFAR3
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.569
IL23A
Interleukin 23 subunit alpha.
  
     0.502
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
   
  
 0.497
BIRC7
Baculoviral IAP repeat containing 7.
      
 0.489
FAM3B
Uncharacterized protein.
      
 0.476
KRT25
Keratin 25; Belongs to the intermediate filament family.
  
 
 
 0.460
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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