Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPR6G protein-coupled receptor 6; Belongs to the G-protein coupled receptor 1 family. (378 aa)    
Predicted Functional Partners:
GPR88
G protein-coupled receptor 88.
   
  
 0.763
CHRM4
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
   
 
 0.641
GPR55
G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family.
     
 0.639
PDYN
Prodynorphin.
   
 0.629
TAC1
C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family.
   
 
 0.622
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.610
ARPP21
cAMP regulated phosphoprotein 21.
   
  
 0.595
PENK
Uncharacterized protein.
    
 0.559
PDE10A
Phosphodiesterase.
   
  
 0.534
TMEM211
Uncharacterized protein.
      
 0.528
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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