| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGEF3 | KREMEN1 | ENSOCUP00000011425 | ENSOCUP00000008360 | Rho guanine nucleotide exchange factor 3. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.585 |
| ASGR1 | KREMEN1 | ENSOCUP00000024133 | ENSOCUP00000008360 | Asialoglycoprotein receptor 1. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.804 |
| CENPX | FANCM | ENSOCUP00000016934 | ENSOCUP00000006526 | Uncharacterized protein. | FA complementation group M. | 0.995 |
| CENPX | KREMEN1 | ENSOCUP00000016934 | ENSOCUP00000008360 | Uncharacterized protein. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.642 |
| DKK1 | DKK2 | ENSOCUP00000009874 | ENSOCUP00000001514 | Dickkopf-like protein 1. | Dickkopf WNT signaling pathway inhibitor 2. | 0.924 |
| DKK1 | DKK3 | ENSOCUP00000009874 | ENSOCUP00000034404 | Dickkopf-like protein 1. | Dickkopf WNT signaling pathway inhibitor 3. | 0.872 |
| DKK1 | KREMEN1 | ENSOCUP00000009874 | ENSOCUP00000008360 | Dickkopf-like protein 1. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.977 |
| DKK1 | LRP6 | ENSOCUP00000009874 | ENSOCUP00000002615 | Dickkopf-like protein 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.998 |
| DKK1 | ZNRF3 | ENSOCUP00000009874 | ENSOCUP00000048321 | Dickkopf-like protein 1. | Zinc and ring finger 3. | 0.475 |
| DKK2 | DKK1 | ENSOCUP00000001514 | ENSOCUP00000009874 | Dickkopf WNT signaling pathway inhibitor 2. | Dickkopf-like protein 1. | 0.924 |
| DKK2 | DKK3 | ENSOCUP00000001514 | ENSOCUP00000034404 | Dickkopf WNT signaling pathway inhibitor 2. | Dickkopf WNT signaling pathway inhibitor 3. | 0.880 |
| DKK2 | KREMEN1 | ENSOCUP00000001514 | ENSOCUP00000008360 | Dickkopf WNT signaling pathway inhibitor 2. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.852 |
| DKK2 | LRP6 | ENSOCUP00000001514 | ENSOCUP00000002615 | Dickkopf WNT signaling pathway inhibitor 2. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.981 |
| DKK3 | DKK1 | ENSOCUP00000034404 | ENSOCUP00000009874 | Dickkopf WNT signaling pathway inhibitor 3. | Dickkopf-like protein 1. | 0.872 |
| DKK3 | DKK2 | ENSOCUP00000034404 | ENSOCUP00000001514 | Dickkopf WNT signaling pathway inhibitor 3. | Dickkopf WNT signaling pathway inhibitor 2. | 0.880 |
| DKK3 | KREMEN1 | ENSOCUP00000034404 | ENSOCUP00000008360 | Dickkopf WNT signaling pathway inhibitor 3. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.623 |
| DKK3 | LRP6 | ENSOCUP00000034404 | ENSOCUP00000002615 | Dickkopf WNT signaling pathway inhibitor 3. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.600 |
| FANCM | CENPX | ENSOCUP00000006526 | ENSOCUP00000016934 | FA complementation group M. | Uncharacterized protein. | 0.995 |
| FANCM | KREMEN1 | ENSOCUP00000006526 | ENSOCUP00000008360 | FA complementation group M. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.926 |
| KREMEN1 | ARHGEF3 | ENSOCUP00000008360 | ENSOCUP00000011425 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | Rho guanine nucleotide exchange factor 3. | 0.585 |
