Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEK2NIMA related kinase 2. (451 aa)    
Predicted Functional Partners:
BUB1B
Uncharacterized protein.
   
 0.997
CDC20B
Cell division cycle 20B.
   
 0.993
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.988
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 0.987
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.986
NDC80
NDC80 kinetochore complex component.
   
 
 0.975
CDC26
Cell division cycle 26.
    
 0.970
PLK1
Serine/threonine-protein kinase PLK.
   
 
0.965
CDC27
Cell division cycle 27.
    
 0.965
CDC16
Cell division cycle 16.
    
 0.961
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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