HCK protein (Oryctolagus cuniculus) - STRING interaction network

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Score

HCK

Tyrosine-protein kinase. (525 aa)

Predicted Functional Partners:

ZAP70

0.964

PTPRC

0.959

LYN

0.950

CD4

0.945

CD8A

0.945

FYN

0.938

CBL

0.931

SYK

0.903

CBLB

0.893

PIK3CB

0.892

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	CBLB	ENSOCUP00000004160	ENSOCUP00000004853	Cbl proto-oncogene.	Cbl proto-oncogene B.	0.967
CBL	FYN	ENSOCUP00000004160	ENSOCUP00000013559	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.991
CBL	HCK	ENSOCUP00000004160	ENSOCUP00000008404	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.931
CBL	LYN	ENSOCUP00000004160	ENSOCUP00000002661	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.973
CBL	PIK3CB	ENSOCUP00000004160	ENSOCUP00000004241	Cbl proto-oncogene.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.971
CBL	SYK	ENSOCUP00000004160	ENSOCUP00000015068	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.990
CBL	ZAP70	ENSOCUP00000004160	ENSOCUP00000005043	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.990
CBLB	CBL	ENSOCUP00000004853	ENSOCUP00000004160	Cbl proto-oncogene B.	Cbl proto-oncogene.	0.967
CBLB	FYN	ENSOCUP00000004853	ENSOCUP00000013559	Cbl proto-oncogene B.	Tyrosine-protein kinase.	0.928
CBLB	HCK	ENSOCUP00000004853	ENSOCUP00000008404	Cbl proto-oncogene B.	Tyrosine-protein kinase.	0.893
CBLB	LYN	ENSOCUP00000004853	ENSOCUP00000002661	Cbl proto-oncogene B.	Tyrosine-protein kinase.	0.834
CBLB	PIK3CB	ENSOCUP00000004853	ENSOCUP00000004241	Cbl proto-oncogene B.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.943
CBLB	SYK	ENSOCUP00000004853	ENSOCUP00000015068	Cbl proto-oncogene B.	Tyrosine-protein kinase.	0.960
CBLB	ZAP70	ENSOCUP00000004853	ENSOCUP00000005043	Cbl proto-oncogene B.	Tyrosine-protein kinase.	0.965
CD4	CD8A	ENSOCUP00000030708	ENSOCUP00000045245	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein.	0.992
CD4	FYN	ENSOCUP00000030708	ENSOCUP00000013559	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.771
CD4	HCK	ENSOCUP00000030708	ENSOCUP00000008404	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.945
CD4	LYN	ENSOCUP00000030708	ENSOCUP00000002661	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.825
CD4	PIK3CB	ENSOCUP00000030708	ENSOCUP00000004241	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.501
CD4	PTPRC	ENSOCUP00000030708	ENSOCUP00000010311	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Protein tyrosine phosphatase receptor type C.	0.859