NUMBL protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

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Score

NUMBL

NUMB like endocytic adaptor protein. (672 aa)

Predicted Functional Partners:

NOTCH2

0.968

NOTCH4

0.956

NUMB

0.903

ITCH

0.884

BMP2K

0.851

AP2A1

0.846

EPS15

0.812

GAK

0.779

LNX1

0.770

ITGB1

0.753

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A1	BMP2K	ENSOCUP00000043317	ENSOCUP00000009959	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	BMP2 inducible kinase.	0.619
AP2A1	EPS15	ENSOCUP00000043317	ENSOCUP00000003714	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Epidermal growth factor receptor pathway substrate 15.	0.955
AP2A1	GAK	ENSOCUP00000043317	ENSOCUP00000002563	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Cyclin G associated kinase.	0.993
AP2A1	NUMB	ENSOCUP00000043317	ENSOCUP00000009218	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	NUMB endocytic adaptor protein.	0.853
AP2A1	NUMBL	ENSOCUP00000043317	ENSOCUP00000008438	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	NUMB like endocytic adaptor protein.	0.846
BMP2K	AP2A1	ENSOCUP00000009959	ENSOCUP00000043317	BMP2 inducible kinase.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.619
BMP2K	EPS15	ENSOCUP00000009959	ENSOCUP00000003714	BMP2 inducible kinase.	Epidermal growth factor receptor pathway substrate 15.	0.735
BMP2K	GAK	ENSOCUP00000009959	ENSOCUP00000002563	BMP2 inducible kinase.	Cyclin G associated kinase.	0.832
BMP2K	NUMB	ENSOCUP00000009959	ENSOCUP00000009218	BMP2 inducible kinase.	NUMB endocytic adaptor protein.	0.851
BMP2K	NUMBL	ENSOCUP00000009959	ENSOCUP00000008438	BMP2 inducible kinase.	NUMB like endocytic adaptor protein.	0.851
EPS15	AP2A1	ENSOCUP00000003714	ENSOCUP00000043317	Epidermal growth factor receptor pathway substrate 15.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.955
EPS15	BMP2K	ENSOCUP00000003714	ENSOCUP00000009959	Epidermal growth factor receptor pathway substrate 15.	BMP2 inducible kinase.	0.735
EPS15	GAK	ENSOCUP00000003714	ENSOCUP00000002563	Epidermal growth factor receptor pathway substrate 15.	Cyclin G associated kinase.	0.914
EPS15	NUMB	ENSOCUP00000003714	ENSOCUP00000009218	Epidermal growth factor receptor pathway substrate 15.	NUMB endocytic adaptor protein.	0.841
EPS15	NUMBL	ENSOCUP00000003714	ENSOCUP00000008438	Epidermal growth factor receptor pathway substrate 15.	NUMB like endocytic adaptor protein.	0.812
GAK	AP2A1	ENSOCUP00000002563	ENSOCUP00000043317	Cyclin G associated kinase.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.993
GAK	BMP2K	ENSOCUP00000002563	ENSOCUP00000009959	Cyclin G associated kinase.	BMP2 inducible kinase.	0.832
GAK	EPS15	ENSOCUP00000002563	ENSOCUP00000003714	Cyclin G associated kinase.	Epidermal growth factor receptor pathway substrate 15.	0.914
GAK	NUMB	ENSOCUP00000002563	ENSOCUP00000009218	Cyclin G associated kinase.	NUMB endocytic adaptor protein.	0.772
GAK	NUMBL	ENSOCUP00000002563	ENSOCUP00000008438	Cyclin G associated kinase.	NUMB like endocytic adaptor protein.	0.779