| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQP11 | AQP2 | ENSOCUP00000043459 | ENSOCUP00000047709 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.834 |
| AQP11 | AQP4 | ENSOCUP00000043459 | ENSOCUP00000007625 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.893 |
| AQP11 | AQP6 | ENSOCUP00000043459 | ENSOCUP00000022532 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.916 |
| AQP11 | AQP8 | ENSOCUP00000043459 | ENSOCUP00000001602 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.938 |
| AQP11 | AQP9 | ENSOCUP00000043459 | ENSOCUP00000008440 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.871 |
| AQP11 | GHRHR | ENSOCUP00000043459 | ENSOCUP00000039036 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.726 |
| AQP11 | MIP | ENSOCUP00000043459 | ENSOCUP00000017555 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.714 |
| AQP2 | AQP11 | ENSOCUP00000047709 | ENSOCUP00000043459 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.834 |
| AQP2 | AQP4 | ENSOCUP00000047709 | ENSOCUP00000007625 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.484 |
| AQP2 | AQP8 | ENSOCUP00000047709 | ENSOCUP00000001602 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.708 |
| AQP2 | AQP9 | ENSOCUP00000047709 | ENSOCUP00000008440 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.714 |
| AQP2 | GHRHR | ENSOCUP00000047709 | ENSOCUP00000039036 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.521 |
| AQP2 | GK | ENSOCUP00000047709 | ENSOCUP00000039978 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein; Belongs to the FGGY kinase family. | 0.429 |
| AQP2 | KATNAL2 | ENSOCUP00000047709 | ENSOCUP00000042461 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | 0.528 |
| AQP2 | MIP | ENSOCUP00000047709 | ENSOCUP00000017555 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.517 |
| AQP4 | AQP11 | ENSOCUP00000007625 | ENSOCUP00000043459 | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.893 |
| AQP4 | AQP2 | ENSOCUP00000007625 | ENSOCUP00000047709 | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.484 |
| AQP4 | AQP6 | ENSOCUP00000007625 | ENSOCUP00000022532 | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.559 |
| AQP4 | AQP8 | ENSOCUP00000007625 | ENSOCUP00000001602 | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.729 |
| AQP4 | AQP9 | ENSOCUP00000007625 | ENSOCUP00000008440 | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.678 |