node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP4E1 | AP4M1 | ENSOCUP00000037934 | ENSOCUP00000000267 | Adaptor related protein complex 4 subunit epsilon 1. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.999 |
AP4E1 | APBB3 | ENSOCUP00000037934 | ENSOCUP00000008459 | Adaptor related protein complex 4 subunit epsilon 1. | Amyloid beta precursor protein binding family B member 3. | 0.653 |
AP4E1 | APP | ENSOCUP00000037934 | ENSOCUP00000009130 | Adaptor related protein complex 4 subunit epsilon 1. | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.570 |
AP4E1 | SPPL2A | ENSOCUP00000037934 | ENSOCUP00000029677 | Adaptor related protein complex 4 subunit epsilon 1. | Signal peptide peptidase like 2A. | 0.735 |
AP4M1 | AP4E1 | ENSOCUP00000000267 | ENSOCUP00000037934 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Adaptor related protein complex 4 subunit epsilon 1. | 0.999 |
AP4M1 | APBB3 | ENSOCUP00000000267 | ENSOCUP00000008459 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Amyloid beta precursor protein binding family B member 3. | 0.672 |
AP4M1 | APP | ENSOCUP00000000267 | ENSOCUP00000009130 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.565 |
AP4M1 | SPPL2A | ENSOCUP00000000267 | ENSOCUP00000029677 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Signal peptide peptidase like 2A. | 0.501 |
APBB3 | AP4E1 | ENSOCUP00000008459 | ENSOCUP00000037934 | Amyloid beta precursor protein binding family B member 3. | Adaptor related protein complex 4 subunit epsilon 1. | 0.653 |
APBB3 | AP4M1 | ENSOCUP00000008459 | ENSOCUP00000000267 | Amyloid beta precursor protein binding family B member 3. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.672 |
APBB3 | APP | ENSOCUP00000008459 | ENSOCUP00000009130 | Amyloid beta precursor protein binding family B member 3. | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.872 |
APBB3 | LIMCH1 | ENSOCUP00000008459 | ENSOCUP00000013367 | Amyloid beta precursor protein binding family B member 3. | LIM and calponin homology domains 1. | 0.614 |
APBB3 | PCDHB1 | ENSOCUP00000008459 | ENSOCUP00000006401 | Amyloid beta precursor protein binding family B member 3. | Protocadherin beta 1. | 0.624 |
APBB3 | PKP4 | ENSOCUP00000008459 | ENSOCUP00000011583 | Amyloid beta precursor protein binding family B member 3. | Plakophilin 4. | 0.583 |
APBB3 | PRDM5 | ENSOCUP00000008459 | ENSOCUP00000011579 | Amyloid beta precursor protein binding family B member 3. | Zinc finger protein. | 0.576 |
APBB3 | SCPEP1 | ENSOCUP00000008459 | ENSOCUP00000009770 | Amyloid beta precursor protein binding family B member 3. | Carboxypeptidase; Belongs to the peptidase S10 family. | 0.601 |
APBB3 | SPPL2A | ENSOCUP00000008459 | ENSOCUP00000029677 | Amyloid beta precursor protein binding family B member 3. | Signal peptide peptidase like 2A. | 0.561 |
APBB3 | THYN1 | ENSOCUP00000008459 | ENSOCUP00000037304 | Amyloid beta precursor protein binding family B member 3. | Thymocyte nuclear protein 1. | 0.641 |
APP | AP4E1 | ENSOCUP00000009130 | ENSOCUP00000037934 | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Adaptor related protein complex 4 subunit epsilon 1. | 0.570 |
APP | AP4M1 | ENSOCUP00000009130 | ENSOCUP00000000267 | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.565 |