PHYHIP protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PHYHIP

Phytanoyl-CoA 2-hydroxylase interacting protein. (429 aa)

Predicted Functional Partners:

CALHM2

0.599

FAM78A

0.594

GJD4

0.573

TCF23

0.573

NABP1

0.567

SLC26A10

0.557

ASB5

0.553

RASL11A

0.552

LIMS2

0.545

POLR3H

0.544

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB5	CALHM2	ENSOCUP00000010841	ENSOCUP00000005477	Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis.	Calcium homeostasis modulator family member 2.	0.599
ASB5	PHYHIP	ENSOCUP00000010841	ENSOCUP00000008531	Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis.	Phytanoyl-CoA 2-hydroxylase interacting protein.	0.553
ASB5	POLR3H	ENSOCUP00000010841	ENSOCUP00000006287	Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis.	RNA polymerase III subunit H.	0.545
CALHM2	ASB5	ENSOCUP00000005477	ENSOCUP00000010841	Calcium homeostasis modulator family member 2.	Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis.	0.599
CALHM2	PHYHIP	ENSOCUP00000005477	ENSOCUP00000008531	Calcium homeostasis modulator family member 2.	Phytanoyl-CoA 2-hydroxylase interacting protein.	0.599
CALHM2	POLR3H	ENSOCUP00000005477	ENSOCUP00000006287	Calcium homeostasis modulator family member 2.	RNA polymerase III subunit H.	0.569
FAM78A	GJD4	ENSOCUP00000005851	ENSOCUP00000002142	Family with sequence similarity 78 member A.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.593
FAM78A	LIMS2	ENSOCUP00000005851	ENSOCUP00000045634	Family with sequence similarity 78 member A.	LIM zinc finger domain containing 2.	0.558
FAM78A	PHYHIP	ENSOCUP00000005851	ENSOCUP00000008531	Family with sequence similarity 78 member A.	Phytanoyl-CoA 2-hydroxylase interacting protein.	0.594
FAM78A	RASL11A	ENSOCUP00000005851	ENSOCUP00000007020	Family with sequence similarity 78 member A.	RAS like family 11 member A.	0.604
FAM78A	SLC26A10	ENSOCUP00000005851	ENSOCUP00000037430	Family with sequence similarity 78 member A.	Solute carrier family 26 member 10.	0.541
FAM78A	TCF23	ENSOCUP00000005851	ENSOCUP00000007477	Family with sequence similarity 78 member A.	BHLH domain-containing protein.	0.608
GJD4	FAM78A	ENSOCUP00000002142	ENSOCUP00000005851	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Family with sequence similarity 78 member A.	0.593
GJD4	LIMS2	ENSOCUP00000002142	ENSOCUP00000045634	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	LIM zinc finger domain containing 2.	0.553
GJD4	PHYHIP	ENSOCUP00000002142	ENSOCUP00000008531	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Phytanoyl-CoA 2-hydroxylase interacting protein.	0.573
GJD4	RASL11A	ENSOCUP00000002142	ENSOCUP00000007020	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	RAS like family 11 member A.	0.551
GJD4	SLC26A10	ENSOCUP00000002142	ENSOCUP00000037430	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Solute carrier family 26 member 10.	0.558
GJD4	TCF23	ENSOCUP00000002142	ENSOCUP00000007477	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	BHLH domain-containing protein.	0.569
LIMS2	FAM78A	ENSOCUP00000045634	ENSOCUP00000005851	LIM zinc finger domain containing 2.	Family with sequence similarity 78 member A.	0.558
LIMS2	GJD4	ENSOCUP00000045634	ENSOCUP00000002142	LIM zinc finger domain containing 2.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.553