Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF40Rho guanine nucleotide exchange factor 40. (1563 aa)    
Predicted Functional Partners:
ARHGEF37
Rho guanine nucleotide exchange factor 37.
     
 0.675
ARHGAP44
Rho GTPase activating protein 44.
      
 0.647
ARHGAP42
Rho GTPase activating protein 42.
      
 0.644
ARHGEF5
Rho guanine nucleotide exchange factor 5.
     
 0.619
FGD4
FYVE, RhoGEF and PH domain containing 4.
     
 0.607
SLITRK4
SLIT and NTRK like family member 4.
      
 0.594
LGSN
Lengsin; May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity (By similarity); Belongs to the glutamine synthetase family.
      
 0.560
ARHGAP9
Rho GTPase activating protein 9.
      
 0.529
RAPH1
Uncharacterized protein.
      
 0.499
KRT18
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 0.492
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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