STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (609 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.988
RAD21
RAD21 cohesin complex component.
   
 0.951
PDS5A
PDS5 cohesin associated factor A.
   
 0.951
PDS5B
PDS5 cohesin associated factor B.
   
 0.937
WAPL
WAPL cohesin release factor.
   
 
 0.931
SMC1A
SMC hinge domain-containing protein.
   
 0.904
NIPBL
Nipped-B protein.
   
 
 0.853
SMC2
Structural maintenance of chromosomes 2.
   
 0.850
REC8
REC8 meiotic recombination protein.
   
 0.849
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.848
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (38%) [HD]