NPY1R protein (Oryctolagus cuniculus) - STRING interaction network

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Score

NPY1R

Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)

Predicted Functional Partners:

NPY

0.995

PYY

0.956

GNAI1

0.935

GNAI3

0.935

GNAI2

0.932

PPY

0.867

SST

0.845

GHRL

0.760

EDN1

0.701

EDN3

0.699

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDN1	EDN3	ENSOCUP00000011526	ENSOCUP00000046269	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	0.965
EDN1	GHRL	ENSOCUP00000011526	ENSOCUP00000029787	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Uncharacterized protein.	0.467
EDN1	GNAI1	ENSOCUP00000011526	ENSOCUP00000000882	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	G protein subunit alpha i1.	0.403
EDN1	NPY	ENSOCUP00000011526	ENSOCUP00000009261	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.426
EDN1	NPY1R	ENSOCUP00000011526	ENSOCUP00000008576	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.701
EDN3	EDN1	ENSOCUP00000046269	ENSOCUP00000011526	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.965
EDN3	NPY1R	ENSOCUP00000046269	ENSOCUP00000008576	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.699
GHRL	EDN1	ENSOCUP00000029787	ENSOCUP00000011526	Uncharacterized protein.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.467
GHRL	NPY	ENSOCUP00000029787	ENSOCUP00000009261	Uncharacterized protein.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.933
GHRL	NPY1R	ENSOCUP00000029787	ENSOCUP00000008576	Uncharacterized protein.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.760
GHRL	PPY	ENSOCUP00000029787	ENSOCUP00000025326	Uncharacterized protein.	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family.	0.895
GHRL	PYY	ENSOCUP00000029787	ENSOCUP00000011243	Uncharacterized protein.	Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.	0.933
GHRL	SST	ENSOCUP00000029787	ENSOCUP00000006540	Uncharacterized protein.	Somatostatin.	0.887
GNAI1	EDN1	ENSOCUP00000000882	ENSOCUP00000011526	G protein subunit alpha i1.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.403
GNAI1	GNAI2	ENSOCUP00000000882	ENSOCUP00000019624	G protein subunit alpha i1.	G protein subunit alpha i2.	0.973
GNAI1	GNAI3	ENSOCUP00000000882	ENSOCUP00000004821	G protein subunit alpha i1.	G protein subunit alpha i3.	0.902
GNAI1	NPY1R	ENSOCUP00000000882	ENSOCUP00000008576	G protein subunit alpha i1.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.935
GNAI2	GNAI1	ENSOCUP00000019624	ENSOCUP00000000882	G protein subunit alpha i2.	G protein subunit alpha i1.	0.973
GNAI2	GNAI3	ENSOCUP00000019624	ENSOCUP00000004821	G protein subunit alpha i2.	G protein subunit alpha i3.	0.973
GNAI2	NPY1R	ENSOCUP00000019624	ENSOCUP00000008576	G protein subunit alpha i2.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.932