STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP2PH domain and leucine rich repeat protein phosphatase 2. (1356 aa)    
Predicted Functional Partners:
AKT3
Non-specific serine/threonine protein kinase.
    
 0.992
AKT2
AKT serine/threonine kinase 2.
    
 0.862
USP46
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.817
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.765
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 
 0.762
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.762
WDR20
WD repeat domain 20.
    
 
 0.747
USP12
Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family.
   
 
 0.717
G1TX42_RABIT
CAP_N domain-containing protein.
    
 
 0.693
WDR48
WD repeat domain 48.
    
 
 0.632
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.