LMNA protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LMNA

Lamin A/C; Belongs to the intermediate filament family. (704 aa)

Predicted Functional Partners:

LMNB1

0.995

EMD

0.994

CASP6

0.978

SUN2

0.965

BANF1

0.923

TMPO

0.915

SYNE1

0.913

LOC103351183

0.907

SYNE2

0.893

ENSOCUP00000048359

0.893

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BANF1	EMD	ENSOCUP00000013518	ENSOCUP00000035373	Uncharacterized protein.	Emerin (Predicted).	0.996
BANF1	LMNA	ENSOCUP00000013518	ENSOCUP00000008626	Uncharacterized protein.	Lamin A/C; Belongs to the intermediate filament family.	0.923
BANF1	LMNB1	ENSOCUP00000013518	ENSOCUP00000006488	Uncharacterized protein.	Lamin B1; Belongs to the intermediate filament family.	0.949
BANF1	SUN2	ENSOCUP00000013518	ENSOCUP00000016388	Uncharacterized protein.	Sad1 and UNC84 domain containing 2.	0.529
BANF1	TMPO	ENSOCUP00000013518	ENSOCUP00000038289	Uncharacterized protein.	Thymopoietin.	0.787
CASP6	LMNA	ENSOCUP00000011835	ENSOCUP00000008626	Caspase 6; Belongs to the phospholipase A2 family.	Lamin A/C; Belongs to the intermediate filament family.	0.978
CASP6	LMNB1	ENSOCUP00000011835	ENSOCUP00000006488	Caspase 6; Belongs to the phospholipase A2 family.	Lamin B1; Belongs to the intermediate filament family.	0.976
EMD	BANF1	ENSOCUP00000035373	ENSOCUP00000013518	Emerin (Predicted).	Uncharacterized protein.	0.996
EMD	ENSOCUP00000048359	ENSOCUP00000035373	ENSOCUP00000048359	Emerin (Predicted).	Uncharacterized protein.	0.943
EMD	LMNA	ENSOCUP00000035373	ENSOCUP00000008626	Emerin (Predicted).	Lamin A/C; Belongs to the intermediate filament family.	0.994
EMD	LMNB1	ENSOCUP00000035373	ENSOCUP00000006488	Emerin (Predicted).	Lamin B1; Belongs to the intermediate filament family.	0.962
EMD	SUN2	ENSOCUP00000035373	ENSOCUP00000016388	Emerin (Predicted).	Sad1 and UNC84 domain containing 2.	0.958
EMD	SYNE1	ENSOCUP00000035373	ENSOCUP00000027005	Emerin (Predicted).	Spectrin repeat containing nuclear envelope protein 1.	0.965
EMD	SYNE2	ENSOCUP00000035373	ENSOCUP00000039833	Emerin (Predicted).	KASH domain-containing protein.	0.962
EMD	TMPO	ENSOCUP00000035373	ENSOCUP00000038289	Emerin (Predicted).	Thymopoietin.	0.752
ENSOCUP00000048359	EMD	ENSOCUP00000048359	ENSOCUP00000035373	Uncharacterized protein.	Emerin (Predicted).	0.943
ENSOCUP00000048359	LMNA	ENSOCUP00000048359	ENSOCUP00000008626	Uncharacterized protein.	Lamin A/C; Belongs to the intermediate filament family.	0.893
ENSOCUP00000048359	LMNB1	ENSOCUP00000048359	ENSOCUP00000006488	Uncharacterized protein.	Lamin B1; Belongs to the intermediate filament family.	0.787
ENSOCUP00000048359	TMPO	ENSOCUP00000048359	ENSOCUP00000038289	Uncharacterized protein.	Thymopoietin.	0.421
LMNA	BANF1	ENSOCUP00000008626	ENSOCUP00000013518	Lamin A/C; Belongs to the intermediate filament family.	Uncharacterized protein.	0.923