Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF41Ring finger protein 41. (317 aa)    
Predicted Functional Partners:
USP8
Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.
    
 0.988
ERBB3
Erb-b2 receptor tyrosine kinase 3.
   
 0.982
ERBB4
Receptor protein-tyrosine kinase.
    
 0.943
VPS52
VPS52 subunit of GARP complex.
   
 
 0.937
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.925
EGFR
Receptor protein-tyrosine kinase.
    
 0.925
WWP1
E3 ubiquitin-protein ligase.
    
 0.887
IGF1R
Tyrosine-protein kinase receptor.
   
  0.887
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 0.883
CBL
Cbl proto-oncogene.
   
 0.870
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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