| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIRC3 | CASP3 | ENSOCUP00000008710 | ENSOCUP00000036614 | Baculoviral IAP repeat containing 3. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | 0.984 |
| BIRC3 | CASP7 | ENSOCUP00000008710 | ENSOCUP00000009498 | Baculoviral IAP repeat containing 3. | Caspase 7; Belongs to the peptidase C14A family. | 0.975 |
| BIRC3 | CASP9 | ENSOCUP00000008710 | ENSOCUP00000047129 | Baculoviral IAP repeat containing 3. | Caspase 9; Belongs to the peptidase C14A family. | 0.982 |
| BIRC3 | DIABLO | ENSOCUP00000008710 | ENSOCUP00000022338 | Baculoviral IAP repeat containing 3. | Uncharacterized protein. | 0.985 |
| BIRC3 | MAP3K7 | ENSOCUP00000008710 | ENSOCUP00000001455 | Baculoviral IAP repeat containing 3. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.984 |
| BIRC3 | RIPK1 | ENSOCUP00000008710 | ENSOCUP00000010138 | Baculoviral IAP repeat containing 3. | Receptor interacting serine/threonine kinase 1. | 0.987 |
| BIRC3 | RIPK2 | ENSOCUP00000008710 | ENSOCUP00000001326 | Baculoviral IAP repeat containing 3. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.968 |
| BIRC3 | TNFRSF1A | ENSOCUP00000008710 | ENSOCUP00000045661 | Baculoviral IAP repeat containing 3. | TNF receptor superfamily member 1A. | 0.989 |
| BIRC3 | TRADD | ENSOCUP00000008710 | ENSOCUP00000018718 | Baculoviral IAP repeat containing 3. | TNFRSF1A associated via death domain. | 0.980 |
| BIRC3 | TRAF3 | ENSOCUP00000008710 | ENSOCUP00000003184 | Baculoviral IAP repeat containing 3. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.978 |
| CASP3 | BIRC3 | ENSOCUP00000036614 | ENSOCUP00000008710 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Baculoviral IAP repeat containing 3. | 0.984 |
| CASP3 | CASP7 | ENSOCUP00000036614 | ENSOCUP00000009498 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Caspase 7; Belongs to the peptidase C14A family. | 0.969 |
| CASP3 | CASP9 | ENSOCUP00000036614 | ENSOCUP00000047129 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Caspase 9; Belongs to the peptidase C14A family. | 0.996 |
| CASP3 | DIABLO | ENSOCUP00000036614 | ENSOCUP00000022338 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Uncharacterized protein. | 0.768 |
| CASP3 | RIPK1 | ENSOCUP00000036614 | ENSOCUP00000010138 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 1. | 0.914 |
| CASP3 | TNFRSF1A | ENSOCUP00000036614 | ENSOCUP00000045661 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | TNF receptor superfamily member 1A. | 0.578 |
| CASP3 | TRADD | ENSOCUP00000036614 | ENSOCUP00000018718 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | TNFRSF1A associated via death domain. | 0.831 |
| CASP3 | TRAF3 | ENSOCUP00000036614 | ENSOCUP00000003184 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.605 |
| CASP7 | BIRC3 | ENSOCUP00000009498 | ENSOCUP00000008710 | Caspase 7; Belongs to the peptidase C14A family. | Baculoviral IAP repeat containing 3. | 0.975 |
| CASP7 | CASP3 | ENSOCUP00000009498 | ENSOCUP00000036614 | Caspase 7; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | 0.969 |