Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MKRN1Makorin ring finger protein 1. (479 aa)    
Predicted Functional Partners:
ECD
Ecdysoneless cell cycle regulator.
      
 0.678
FAM131B
Family with sequence similarity 131 member B.
      
 0.640
TRIP12
Thyroid hormone receptor interactor 12.
     
 0.620
RBBP6
RB binding protein 6, ubiquitin ligase.
     
 0.576
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.572
UBE2D1
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.566
UBOX5
U-box domain containing 5.
     
 0.565
G1SK22_RABIT
Ubiquitin-like domain-containing protein.
   
  0.558
G1TZL0_RABIT
Ubiquitin-like domain-containing protein.
   
  0.558
IGF2BP3
Insulin like growth factor 2 mRNA binding protein 3.
    
 
 0.536
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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