| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARNT | BNIP3 | ENSOCUP00000037075 | ENSOCUP00000002192 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | BCL2 interacting protein 3. | 0.683 |
| ARNT | CA9 | ENSOCUP00000037075 | ENSOCUP00000008783 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | 0.715 |
| ARNT | EGLN3 | ENSOCUP00000037075 | ENSOCUP00000007394 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | Fe2OG dioxygenase domain-containing protein. | 0.635 |
| ARNT | HIF1A | ENSOCUP00000037075 | ENSOCUP00000041090 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | Uncharacterized protein. | 0.997 |
| ARNT | HMOX1 | ENSOCUP00000037075 | ENSOCUP00000009161 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | Heme oxygenase 1. | 0.489 |
| ARNT | LDHA | ENSOCUP00000037075 | ENSOCUP00000013690 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | L-lactate dehydrogenase A chain. | 0.716 |
| ARNT | PGK1 | ENSOCUP00000037075 | ENSOCUP00000012659 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | Phosphoglycerate kinase. | 0.590 |
| ARNT | SLC2A1 | ENSOCUP00000037075 | ENSOCUP00000027075 | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | 0.605 |
| BNIP3 | ARNT | ENSOCUP00000002192 | ENSOCUP00000037075 | BCL2 interacting protein 3. | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | 0.683 |
| BNIP3 | CA9 | ENSOCUP00000002192 | ENSOCUP00000008783 | BCL2 interacting protein 3. | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | 0.624 |
| BNIP3 | EGLN3 | ENSOCUP00000002192 | ENSOCUP00000007394 | BCL2 interacting protein 3. | Fe2OG dioxygenase domain-containing protein. | 0.411 |
| BNIP3 | HIF1A | ENSOCUP00000002192 | ENSOCUP00000041090 | BCL2 interacting protein 3. | Uncharacterized protein. | 0.742 |
| BNIP3 | LDHA | ENSOCUP00000002192 | ENSOCUP00000013690 | BCL2 interacting protein 3. | L-lactate dehydrogenase A chain. | 0.596 |
| BNIP3 | PGK1 | ENSOCUP00000002192 | ENSOCUP00000012659 | BCL2 interacting protein 3. | Phosphoglycerate kinase. | 0.600 |
| BNIP3 | SLC2A1 | ENSOCUP00000002192 | ENSOCUP00000027075 | BCL2 interacting protein 3. | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | 0.528 |
| CA12 | CA9 | ENSOCUP00000031976 | ENSOCUP00000008783 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | 0.552 |
| CA12 | RPF2 | ENSOCUP00000031976 | ENSOCUP00000013776 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog. | 0.604 |
| CA9 | ARNT | ENSOCUP00000008783 | ENSOCUP00000037075 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and funct [...] | 0.715 |
| CA9 | BNIP3 | ENSOCUP00000008783 | ENSOCUP00000002192 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | BCL2 interacting protein 3. | 0.624 |
| CA9 | CA12 | ENSOCUP00000008783 | ENSOCUP00000031976 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.552 |