Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARHGAP25Rho GTPase activating protein 25. (646 aa)    
Predicted Functional Partners:
WAS
WASP actin nucleation promoting factor.
   
 
 0.643
PLD5
Phospholipase D family member 5.
   
  
 0.599
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
   
    0.598
CABCOCO1
Ciliary associated calcium binding coiled-coil 1.
      
 0.564
DNTTIP2
Deoxynucleotidyltransferase terminal interacting protein 2.
      
 0.561
EFCAB5
EF-hand calcium binding domain 5.
    
 0.552
TMEM87A
Transmembrane protein 87A.
      
 0.547
HSD17B14
Hydroxysteroid 17-beta dehydrogenase 14.
      
 0.523
CAPN15
Calpain 15; Belongs to the peptidase C2 family.
      
 0.519
ASB14
Ankyrin repeat and SOCS box containing 14.
      
 0.508
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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